RNA-protein complex refinement using AI modeling and docking
This article explains a workflow for refining protein-RNA complexes by combining AI-based structural models with flexible docking and enhanced sampling.
This article explains a workflow for refining protein-RNA complexes by combining AI-based structural models with flexible docking and enhanced sampling.
Molecular dynamics and binding-energy calculations are used here to compare how Musashi-1 recognizes different RNA motifs and to identify determinants of binding specificity.
This paper shows that many deep learning models for RNA secondary structure prediction learn dataset bias more readily than RNA folding rules, and explains why that matters for the future of AI in RNA biology.