RNA folding kinetics
Posts tagged “RNA folding kinetics”.
BarMap and RNA folding on dynamic energy landscapes
BarMap models RNA folding on changing energy landscapes by linking macrostates between landscape snapshots, enabling efficient analysis of co-transcriptional and externally perturbed folding scenarios.
Folding kinetics of large RNAs
Kinwalker predicts folding trajectories of large RNAs by combining locally optimal substructures and kinetic heuristics, making co-transcriptional folding analysis feasible for molecules up to about 1500 nucleotides.
Efficient computation of RNA folding dynamics
This paper shows how barrier trees and numerical integration can approximate RNA folding dynamics efficiently enough to analyze bistable molecules and RNA switches on biologically relevant timescales.