Functional RNAs in Virology Special Issue
MDPI Viruses has launched a new open-access Special Issue on “Functional RNAs in Virology” to highlight recent advances in understanding how RNAs act as regulatory molecule in viral infection
Showing only posts tagged virology. Show all posts.
Insect-specific flaviviruses evade antiviral RNAi
In this paper, we explore the role of RNA interference (RNAi) in mosquito immunity by comparing viral small interfering RNA (siRNA) profiles across different insect-specific flaviviruses
Xinyang flavivirus is a novel tick-borne Orthoflavivirus
In this paper, we report the discovery of Xinyang flavivirus (XiFV), a novel virus isolated from Haemaphysalis flava ticks in China. Through phylogenetic analysis, we found that XiFV is closely related to other tick-only flaviviruses, such as Mpulungu flavivirus (MPFV) from Zambia and Ngoye virus (NGOV) from Senegal. This positions XiFV in a unique clade of orthoflaviviruses, a group that seems to infect only ticks, without any known vertebrate host
Zika virus: Unlocking cures with G-quadruplex structures
We identified a conserved G-quadruplex structure in the Zika virus's 3' terminal region, which interacts with human DEAD-box helicases, DDX3X and DDX17. These findings suggest new potential therapeutic targets for the development of treatments against the virus
Strukturierte RNAs in Viren (in German)
In this mini-review we discuss the concept of RNA structure conservation in viruses, using exoribonuclease-resistant RNAs from flaviviruses as prominent examples
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