What virus bioinformatics can and cannot tell us about RNA viruses
Virus bioinformatics helps us compare genomes, track outbreaks, and identify conserved RNA elements, but its value depends on careful interpretation rather than broad claims.
Virus bioinformatics helps us compare genomes, track outbreaks, and identify conserved RNA elements, but its value depends on careful interpretation rather than broad claims.
This study examines evidence for a conserved G-quadruplex in the Zika virus 3' terminal region and discusses what the observed DDX17 interaction does, and does not, imply.
This study combines computational and biophysical analysis to characterize a long-range RNA-RNA interaction in Japanese encephalitis virus and to test the role of the conserved cyclization sequence.
In this mini-review we discuss the concept of RNA structure conservation in viruses, using exoribonuclease-resistant RNAs from flaviviruses as prominent examples
This study combines comparative RNA structure analysis with molecular epidemiology to characterize conserved and variable 3' UTR architectures across tick-borne encephalitis virus lineages.