We identified a conserved G-quadruplex structure in the Zika virus's 3' terminal region, which interacts with human DEAD-box helicases, DDX3X and DDX17. These findings suggest new potential therapeutic targets for the development of treatments against the virus
Unraveling the intricate RNA-RNA interactions in Japanese encephalitis virus (JEV) opens new possibilities for understanding viral replication and designing antiviral therapeutics, as our recent study reveals the importance of a conserved cyclization sequence in driving these interactions
In this mini-review we discuss the concept of RNA structure conservation in viruses, using exoribonuclease-resistant RNAs from flaviviruses as prominent examples
In this paper, we study the molecular epidemiology and RNA structureome diversity of tick-borne encephalitis virus (TBEV). Moreover, we propose a unified picture of pervasive non-coding RNA structure conservation across all known TBEV subtypes
The 3'UTR of Mosquito-Borne Flaviviruses (MBF) contain evolutionarily conserved functional elements, such as exoribonuclease-resistant RNAs (xrRNAs), dumbbell elements or terminal stem-loops. In this contribution we describe, annotate, and compare these elements within different serological groups of MBF