Nov 03 2023 The Pivotal Role of Virus Bioinformatics in Global Health

On One Health Day, we recognize the intricate links between human, animal, and environmental health, underscored by the emergence of novel viruses like SARS-CoV-2. This post, crafted for a lay audience, delves into the critical contributions of virus bioinformatics in understanding and combating infectious diseases. It emphasizes the importance of predicting RNA structures for understanding RNA viruses and discusses the role of genomic epidemiology in tracking viral spread and evolution.

Mar 31 2023 RNA–RNA interaction analysis of Japanese encephalitis virus

Unraveling the intricate RNA-RNA interactions in Japanese encephalitis virus (JEV) opens new possibilities for understanding viral replication and designing antiviral therapeutics, as our recent study reveals the importance of a conserved cyclization sequence in driving these interactions

Mar 23 2023 Strukturierte RNAs in Viren (in German)

In this mini-review we discuss the concept of RNA structure conservation in viruses, using exoribonuclease-resistant RNAs from flaviviruses as prominent examples

Feb 03 2022 Japanese encephalitis virus genome cyclization is kinetically driven

This study uses biophysical and bioinformatics methods to assess the long-range RNA-RNA interaction between terminal regions of Japanese encephalitis virus

Dec 17 2021 RNA secondary structure conservation and molecular epidemiology of TBEV

In this paper, we study the molecular epidemiology and RNA structureome diversity of tick-borne encephalitis virus (TBEV). Moreover, we propose a unified picture of pervasive non-coding RNA structure conservation across all known TBEV subtypes