The 3'UTR of Mosquito-Borne Flaviviruses (MBFVs) contain evolutionarily conserved functional elements, such as exoribonuclease-resistant RNAs (xrRNAs), dumbbell elements or terminal stem-loops. In this contribution we describe, annotate, and compare these elements within different serological groups of MBFVs
Here we characterize a pseudoknot in the 5'UTR Internal Ribosome Entry Site (IRES) of Bovine Viral Diarrhea Virus (BVDV) using SHAPE-guided RNA structure probing and computational modelling of secondary and tertiary structures
The discovery of Mpulungu virus (MPFV), a novel tick-borne flavivirus in Zambia, expands our understanding of the geographical distribution and genetic diversity of flaviviruses across Africa. This study delves into the genetic details of MPFV, suggesting its potential to infect vertebrate hosts and underscoring the importance of a One Health approach in addressing emerging infectious diseases
The combination of molecular epidemiology data with RNA structure prediction provides insights into unresolved aspects of genotype-phenotype associations in Chikungunya virus
Discovering the characteristic traits of Musashi Binding Elements (MBEs) in Flaviviruses with a Thermodynamic Model