A comparative genomics analysis of flavivirus 3' UTRs that identifies conserved exoribonuclease-resistant RNAs and lineage-specific architectural variation across tick-borne, insect-specific, and no-known-vector flaviviruses.
A landscape-based method for modeling how cotranscriptional folding and ligand binding interact in kinetically controlled riboswitches, illustrated with the 2'dG riboswitch from Mesoplasma florum.
A computational workflow for designing ligand-triggered RNA switches, with emphasis on sequence design, folding kinetics, and candidate prioritization.
This paper uses NMR spectroscopy to resolve transcription intermediates of the 2'dG riboswitch at single-nucleotide resolution, showing how transcript length and metastable states govern ligand-controlled switching.