Showing only posts tagged non-coding RNA. Show all posts.

Zika virus: Unlocking cures with G-quadruplex structures

We identified a conserved G-quadruplex structure in the Zika virus's 3' terminal region, which interacts with human DEAD-box helicases, DDX3X and DDX17. These findings suggest new potential therapeutic targets for the development of treatments against the virus

RNA–RNA interaction analysis of Japanese encephalitis virus

Unraveling the intricate RNA-RNA interactions in Japanese encephalitis virus (JEV) opens new possibilities for understanding viral replication and designing antiviral therapeutics, as our recent study reveals the importance of a conserved cyclization sequence in driving these interactions

RNA structure conservation and molecular epidemiology of TBEV

In this paper, we study the molecular epidemiology and RNA structureome diversity of tick-borne encephalitis virus (TBEV). Moreover, we propose a unified picture of pervasive non-coding RNA structure conservation across all known TBEV subtypes

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