bacteria
Posts tagged “bacteria”.
Hfq, Crc, and antibiotic resistance in P. aeruginosa
This study examines carbon catabolite repression and its indirect effects on antibiotic susceptibility in Pseudomonas aeruginosa.
How Pseudomonas aeruginosa responds to colistin and tobramycin
This study combines RNA-seq and ribosome profiling to show how Pseudomonas aeruginosa rewires both transcription and translation when challenged with the last-resort antibiotics colistin and tobramycin.
Hfq regulates carbapenem susceptibility in Pseudomonas aeruginosa
This paper shows that the RNA chaperone Hfq controls carbapenem susceptibility in Pseudomonas aeruginosa through two different post-transcriptional routes acting on the porins OprD and OpdP.
Metabolic control of Hfq-dependent antibiotic susceptibility in Pseudomonas aeruginosa
This paper asks whether the Hfq/Crc/CrcZ metabolic control system can be used to make Pseudomonas aeruginosa more sensitive to antibiotics, and shows that the answer is yes.
How Crc modulates Hfq-dependent RNA regulation in Pseudomonas aeruginosa
This paper explains how the catabolite repression protein Crc modulates Hfq-dependent translational control in Pseudomonas aeruginosa by stabilizing Hfq/RNA assemblies and competing with sRNA access to Hfq.