Strukturierte RNAs in Viren (in German)
In this mini-review we discuss the concept of RNA structure conservation in viruses, using exoribonuclease-resistant RNAs from flaviviruses as prominent examples
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The link between mRNA vaccine design and barbeque optimization
The rational design of vaccine mRNAs and barbeque share common traits: Both require extensive optimization and benefit from experience
RNA secondary structure conservation and molecular epidemiology of TBEV
In this paper, we study the molecular epidemiology and RNA structureome diversity of tick-borne encephalitis virus (TBEV). Moreover, we propose a unified picture of pervasive non-coding RNA structure conservation across all known TBEV subtypes
BVDV IRES RNA in focus: A game changer for livestock health
Here we characterize a pseudoknot in the 5'UTR Internal Ribosome Entry Site (IRES) of Bovine Viral Diarrhea Virus (BVDV) using SHAPE-guided RNA structure probing and computational modelling of secondary and tertiary structures
Comparative look at flavivirus UTRs: Similarities and surprises
This study highlights the crucial role of untranslated regions (UTRs) in flaviviruses and the discovery of exoribonuclease resistant RNAs (xrRNAs). These findings showcase the importance of virus bioinformatic studies in advancing our understanding of infectious diseases and their relevance to broader health goals
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