Showing only posts tagged xrRNA. Show all posts.

RNA structure conservation and molecular epidemiology of TBEV

In this paper, we study the molecular epidemiology and RNA structureome diversity of tick-borne encephalitis virus (TBEV). Moreover, we propose a unified picture of pervasive non-coding RNA structure conservation across all known TBEV subtypes

Functional RNA structures in the 3'UTR of Mosquito-Borne Flaviviruses

The 3'UTR of Mosquito-Borne Flaviviruses (MBFVs) contain evolutionarily conserved functional elements, such as exoribonuclease-resistant RNAs (xrRNAs), dumbbell elements or terminal stem-loops. In this contribution we describe, annotate, and compare these elements within different serological groups of MBFVs

Mpulungu Virus: A glimpse into Africa's novel tick-borne flavivirus

The discovery of Mpulungu virus (MPFV), a novel tick-borne flavivirus in Zambia, expands our understanding of the geographical distribution and genetic diversity of flaviviruses across Africa. This study delves into the genetic details of MPFV, suggesting its potential to infect vertebrate hosts and underscoring the importance of a One Health approach in addressing emerging infectious diseases

Comparative look at flavivirus UTRs: Similarities and surprises

This study highlights the crucial role of untranslated regions (UTRs) in flaviviruses and the discovery of exoribonuclease resistant RNAs (xrRNAs). These findings showcase the importance of virus bioinformatic studies in advancing our understanding of infectious diseases and their relevance to broader health goals