Strukturierte RNAs in Viren (in German)
In this mini-review we discuss the concept of RNA structure conservation in viruses, using exoribonuclease-resistant RNAs from flaviviruses as prominent examples
Showing only posts tagged RNA design. Show all posts.
The link between mRNA vaccine design and barbeque optimization
The rational design of vaccine mRNAs and barbeque share common traits: Both require extensive optimization and benefit from experience
In silico design of ligand triggered RNA switches
In the world of synthetic biology, the design of RNA switches holds immense promise for various applications, ranging from diagnostics to therapeutics. This paper presents a comprehensive workflow for designing RNA switches that can dynamically alter their structural conformations in response to specific ligands
RNA structural insights through prediction and probing
This review explores methods for predicting RNA secondary structures by integrating reactivity information from experimental probing data. It highlights the limitations of traditional RNA structure prediction, which typically relies solely on thermodynamic models based on sequences