Rational design of mechanically active RNAs
This Nucleic Acids Research paper shows that synthetic xrRNAs can be designed from topological rules and validated experimentally as mechanically active RNAs.
Showing only posts tagged RNA design. Show all posts.
A first look at rational design of mechanically active RNAs
A preprint-stage note on the design logic behind synthetic xrRNAs and mechanically active RNAs.
Strukturierte RNAs in Viren (in German)
In this mini-review we discuss the concept of RNA structure conservation in viruses, using exoribonuclease-resistant RNAs from flaviviruses as prominent examples
The link between mRNA vaccine design and barbeque optimization
A short podcast appearance on optimization, data sharing, and what mRNA design can teach us about iterative engineering problems.
In silico design of ligand-triggered RNA switches
A computational workflow for designing ligand-triggered RNA switches, with emphasis on sequence design, folding kinetics, and candidate prioritization.
page 1 | older articles »