In this study, we analyzed the evolution and spread of the Chikungunya virus (CHIKV) across Africa by examining 598 whole genome sequences. Our analysis revealed several distinct CHIKV lineages with strong support, providing new insights into the virus's evolutionary history and its movement across regions
Discovering the characteristic traits of Musashi Binding Elements (MBEs) in Flaviviruses with a Thermodynamic Model
This study highlights the crucial role of untranslated regions (UTRs) in flaviviruses and the discovery of exoribonuclease resistant RNAs (xrRNAs). These findings showcase the importance of virus bioinformatic studies in advancing our understanding of infectious diseases and their relevance to broader health goals
Telomerase RNAs are intrinsically difficult to find by homology search methods, even within phylogenetically related groups. This study reports our efforts in annotating telomerase RNAs in the Saccharomycetacea subgroup of yeasts, using the ViennaRNA Package and related tools
Riboswitches are RNA molecules that regulate gene expression by sensing metabolites, presenting an interesting target for synthetic biology applications. We present a computational approach based on ViennaRNA tools to dissect and model RNA-ligand interaction dynamics under kinetic control, enabling simulation of riboswitch folding