The 3'UTR of Mosquito-Borne Flaviviruses (MBF) contain evolutionarily conserved functional elements, such as exoribonuclease-resistant RNAs (xrRNAs), dumbbell elements or terminal stem-loops. In this contribution we describe, annotate, and compare these elements within different serological groups of MBF
Here we characterize a pseudoknot in the 5'UTR Internal Ribosome Entry Site (IRES) of Bovine Viral Diarrhea Virus (BVDV) using SHAPE-guided RNA structure probing and computational modelling of secondary and tertiary structures
The discovery of Mpulungu virus (MPFV), a novel tick-borne flavivirus in Zambia, expands our understanding of the geographical distribution and genetic diversity of flaviviruses across Africa. This study delves into the genetic details of MPFV, suggesting its potential to infect vertebrate hosts and underscoring the importance of a One Health approach in addressing emerging infectious diseases
This research provides a comprehensive analysis of the molecular epidemiology and evolutionary dynamics of Chikungunya virus (CHIKV), uncovering how single nucleotide variants influence viral RNA structures and shape the global spread of the virus
This study shows how superspreading events fueled the first wave of SARS-CoV-2 in Austria. We analyzed viral mutations and traced travel patterns, revealing the impact of superspreading on the course of the outbreak