Biophysical characterisation of human lincRNA-p21 Alu inverted repeats
In this study we determine the tertiary structure of human LincRNA-p21 Alu Inverted Repeats with biophysical and computational approaches
RNA secondary structure conservation and molecular epidemiology of TBEV
In this paper, we study the molecular epidemiology and RNA structureome diversity of tick-borne encephalitis virus (TBEV). Moreover, we propose a unified picture of pervasive non-coding RNA structure conservation across all known TBEV subtypes
Current deep learning methods unable to predict RNA secondary structures
Machine learning of RNA structure is more challenging than you might think. Using synthetic data from ViennaRNA's RNAfold to study the capabilities and shortcomings of neural networks for RNA secondary structure prediction in a controlled setting, we argue that shortcomings in the artificial setting will translate to real data
Functional RNA structures in the 3'UTR of Mosquito-Borne Flaviviruses
The 3'UTR of Mosquito-Borne Flaviviruses (MBFVs) contain evolutionarily conserved functional elements, such as exoribonuclease-resistant RNAs (xrRNAs), dumbbell elements or terminal stem-loops. In this contribution we describe, annotate, and compare these elements within different serological groups of MBFVs
BVDV IRES RNA in focus: A game changer for livestock health
Here we characterize a pseudoknot in the 5'UTR Internal Ribosome Entry Site (IRES) of Bovine Viral Diarrhea Virus (BVDV) using SHAPE-guided RNA structure probing and computational modelling of secondary and tertiary structures
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