virus bioinformatics
Posts tagged “virus bioinformatics”.
Secondary and tertiary structure of the BVDV IRES
This post summarizes what SHAPE-guided modeling and 3D analysis reveal about a pseudoknot in the BVDV internal ribosome entry site and why that matters for IRES function.
Mpulungu virus and unique xrRNAs in a novel African tick flavivirus
This study describes Mpulungu virus, a novel African tick flavivirus, and characterizes unusual exoribonuclease-resistant RNA structures in its 3' UTR.
Molecular epidemiology and RNA structure in Chikungunya virus
Comparative and phylogenetic analysis of CHIKV genomes links lineage-associated single-nucleotide variants to changes in conserved RNA structures.
Genomic epidemiology of SARS-CoV-2 superspreading events in Austria
This study shows how superspreading events shaped the first wave of SARS-CoV-2 in Austria, based on viral mutations and travel-linked transmission patterns.
Insect-specific flaviviruses from Zambia and their exoribonuclease-resistant RNAs
This study isolates two insect-specific flaviviruses from mosquitoes in Zambia and shows that their 3'UTRs contain functional xrRNA-like elements that stall Xrn1.